Effects of interleukin-6 (IL-6) on cytotrophoblastic cells
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چکیده
منابع مشابه
Effects of interleukin-6 (IL-6) on cytotrophoblastic cells.
Tumour invasion and trophoblastic invasion share the same biochemical mediators: the matrix metalloproteinases (MMP) and their inhibitors. In contrast to tumour invasion of a host tissue, trophoblastic invasion during implantation and placentation is stringently controlled both in tissue localization and developmental stage. The factors responsible for these important regulatory processes are u...
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Cytokines are essential modulators of the immune response. In the last decade there has been a number of cytokines considered targets for the development of biological therapies with the goal of blocking their activities and modulate the course of the immune response, primarily in the context of inflammatory diseases. IL-6 was first identified in the mid-1980s [1], but for almost two decades th...
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The proinflammatory cytokine human interleukin-6 (hIL-6) plays an important role in the early and late courses of inflammation, trauma, and wound healing caused by sulfur mustard (HD). Previously, we demonstrated that hIL-6 might be involved in the early event of structural changes of the signal transducer glycoprotein, which indirectly initiates the cascade of events, such as skin irritation a...
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Curcumin has been shown to have numerous cytotoxic effects on cancer stem cells (CSCs). This is due to its suppression of the release of cytokines, particularly interleukin (IL)-6, IL-8 and IL-1, which stimulate CSCs, and also to its effects at multiple sites along CSC pathways, such as Wnt, Notch, Hedgehog and FAK. In spite of its multiple actions targeting CSCs, curcumin has little toxicity a...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 1999
ISSN: 1460-2407
DOI: 10.1093/molehr/5.11.1055